Geoffrey Burnstock Selected Research

Adenosine Triphosphate (ATP)

1/2019	DT-0111: a novel drug-candidate for the treatment of COPD and chronic cough.
1/2018	The involvement of purinergic signalling in obesity.
12/2017	Purinergic drug targets for gastrointestinal disorders.
1/2017	Purinergic Signaling in the Cardiovascular System.
3/2016	P2X ion channel receptors and inflammation.
1/2016	Purinergic Signalling in the Gut.
3/2014	Inhibition of G protein-coupled P2Y2 receptor induced analgesia in a rat model of trigeminal neuropathic pain.
3/2014	Purinergic signalling in the gastrointestinal tract and related organs in health and disease.
1/2014	Purinergic signaling and blood vessels in health and disease.
7/2013	17β-estradiol rapidly attenuates P2X3 receptor-mediated peripheral pain signal transduction via ERα and GPR30.

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Geoffrey Burnstock Research Topics

Disease

17	Pain (Aches) 01/2016 - 11/2003
16	Neoplasms (Cancer) 01/2018 - 08/2003
11	Inflammation (Inflammations) 12/2017 - 01/2004
10	Hypertension (High Blood Pressure) 01/2018 - 03/2002
9	Hypoxia (Hypoxemia) 01/2017 - 10/2003
8	Ganglion Cysts (Ganglion) 05/2011 - 03/2004
7	Thrombosis (Thrombus) 01/2018 - 03/2008
6	Colitis 01/2018 - 09/2004
6	Stroke (Strokes) 01/2018 - 01/2014
6	Ischemia 01/2017 - 03/2002
6	Prostatic Neoplasms (Prostate Cancer) 03/2010 - 09/2004
5	Atherosclerosis 01/2018 - 03/2002
5	Hyperalgesia 01/2017 - 11/2008
5	Melanoma (Melanoma, Malignant) 09/2009 - 08/2003
4	Visceral Pain 01/2018 - 06/2006
4	Neuralgia (Stump Neuralgia) 01/2017 - 06/2006
4	Bone Resorption 10/2011 - 01/2002
3	Chronic Cough 01/2019 - 01/2017
3	Heart Failure 01/2019 - 03/2015
3	Dry Eye Syndromes (Dry Eye Syndrome) 01/2018 - 01/2017
3	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 12/2017 - 11/2009
3	Migraine Disorders (Migraine) 01/2017 - 01/2014
3	Epilepsy (Aura) 01/2017 - 12/2008
3	Parkinson Disease (Parkinson's Disease) 01/2017 - 01/2011
3	Fibrosis (Cirrhosis) 03/2014 - 12/2009
3	Urinary Bladder Neoplasms (Bladder Cancer) 01/2011 - 01/2008
3	Necrosis 09/2009 - 07/2004
2	Reperfusion Injury 08/2022 - 02/2013
2	Mood Disorders (Mood Disorder) 03/2020 - 12/2011
2	Osteoporosis 01/2018 - 01/2017
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2018 - 01/2017
2	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 12/2017 - 01/2017
2	Coronary Artery Disease (Coronary Atherosclerosis) 01/2017 - 03/2015
2	Diabetic Cardiomyopathies 01/2017 - 03/2015
2	Infarction (Infarctions) 01/2017 - 03/2015
2	Syncope (Fainting) 01/2017 - 03/2015
2	Diabetes Mellitus 01/2017 - 04/2008
2	Cardiomyopathies (Cardiomyopathy) 01/2017 - 03/2015
2	Seizures (Absence Seizure) 01/2017 - 12/2008
2	Weight Loss (Weight Reduction) 01/2017 - 09/2009
2	Myocardial Infarction 01/2017 - 12/2015
2	Hypertrophy 03/2015 - 02/2006
2	Wounds and Injuries (Trauma) 01/2011 - 12/2003
2	Erectile Dysfunction 02/2009 - 04/2008
2	Carcinoma (Carcinomatosis) 07/2008 - 05/2005
2	Urinary Bladder Neck Obstruction (Bladder Neck Obstruction) 04/2008 - 02/2006
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 09/2006 - 08/2003
2	Skin Neoplasms (Skin Cancer) 09/2006 - 08/2003
1	Brain Ischemia (Cerebral Ischemia) 08/2022
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2019
1	Cough 01/2019

Drug/Important Bio-Agent (IBA)

45	Adenosine Triphosphate (ATP)IBA 01/2019 - 03/2002
27	Purinergic Receptors (Receptors, Purine)IBA 12/2017 - 04/2003
9	NucleotidesIBA 01/2017 - 01/2002
8	Adenosine (Adenocard)FDA LinkGeneric 01/2019 - 11/2003
8	Purinergic P2X3 ReceptorsIBA 01/2018 - 12/2003
7	Purinergic P2Y2 ReceptorsIBA 01/2018 - 01/2002
6	Ion Channels (Ion Channel)IBA 01/2018 - 12/2003
5	Estrogens (Estrogen)FDA Link 01/2017 - 11/2009
5	PurinesIBA 01/2016 - 06/2003
5	Hormones (Hormone)IBA 02/2009 - 09/2004
4	Messenger RNA (mRNA)IBA 08/2022 - 05/2005
4	Purinergic P2X7 ReceptorsIBA 01/2017 - 08/2003
4	CytokinesIBA 03/2016 - 07/2004
4	PyrimidinesIBA 01/2016 - 06/2003
4	Uridine Triphosphate (UTP)IBA 05/2011 - 01/2002
4	Proteins (Proteins, Gene)FDA Link 06/2009 - 12/2003
4	alpha,beta-methyleneadenosine 5'-triphosphateIBA 11/2008 - 06/2004
3	CalciumIBA 12/2017 - 02/2008
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2017 - 01/2013
3	Estradiol (Delestrogen)FDA LinkGeneric 02/2012 - 11/2009
3	salicylhydroxamic acid (SHAM)IBA 03/2011 - 02/2006
3	Purinergic P2Y1 ReceptorsIBA 06/2005 - 01/2002
2	Pharmaceutical PreparationsIBA 01/2019 - 12/2017
2	Purinergic AgonistsIBA 01/2018 - 01/2008
2	EnzymesIBA 12/2017 - 10/2012
2	purineIBA 01/2017 - 03/2014
2	Purinergic AgentsIBA 01/2017 - 01/2014
2	U 0126 (UO 126)IBA 01/2017 - 07/2013
2	Clopidogrel (Plavix)FDA Link 01/2017 - 12/2015
2	Purinergic P2X1 ReceptorsIBA 03/2014 - 02/2005
2	Estrogen ReceptorsIBA 07/2013 - 11/2009
2	purinoceptor P2Y6IBA 10/2011 - 04/2006
2	Progesterone FDA LinkGeneric 01/2011 - 11/2009
2	Streptozocin (Streptozotocin)FDA Link 05/2009 - 07/2004
2	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 08/2008 - 09/2005
2	Antineoplastic Agents (Antineoplastics)IBA 07/2008 - 01/2008
2	Adenosine Diphosphate (ADP)IBA 04/2008 - 01/2002
2	ParaffinIBA 09/2006 - 08/2003
2	Purinergic P2X2 ReceptorsIBA 03/2004 - 12/2003
1	Thyrotropin-Releasing Hormone (Protirelin)FDA Link 08/2022
1	Peptides (Polypeptides)IBA 08/2022
1	Neurotransmitter Agents (Neurotransmitter)IBA 03/2020
1	NeuropeptidesIBA 01/2019

Therapy/Procedure

4	Therapeutics 01/2019 - 06/2005
3	Ligation 01/2017 - 09/2003
2	Heart Transplantation (Grafting, Heart) 01/2017 - 03/2015
2	Transplantation 03/2014 - 10/2012
2	Orchiectomy (Orchidectomy) 03/2011 - 03/2010
2	Intraperitoneal Injections 09/2009 - 01/2008